H Uri Saragovi Selected Research

trkA Receptor

1/2022	Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies.
6/2007	Neurotrophic rationale in glaucoma: a TrkA agonist, but not NGF or a p75 antagonist, protects retinal ganglion cells in vivo.
12/2005	Progression of age-associated cognitive impairment correlates with quantitative and qualitative loss of TrkA receptor protein in nucleus basalis and cortex.
2/2004	Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension.

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H Uri Saragovi Research Topics

Disease

13	Neoplasms (Cancer) 12/2021 - 06/2004
9	Glaucoma 07/2011 - 02/2004
6	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 10/2004
6	Inflammation (Inflammations) 01/2018 - 10/2013
5	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 09/2004
4	Cognitive Dysfunction 01/2022 - 10/2004
4	Disease Progression 01/2016 - 12/2005
4	Ocular Hypertension (Glaucoma, Suspect) 09/2010 - 02/2004
3	Melanoma (Melanoma, Malignant) 12/2021 - 01/2008
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2018 - 01/2016
3	Edema (Dropsy) 01/2018 - 01/2016
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020 - 12/2017
2	Atrophy 01/2019 - 12/2005
2	Ganglion Cysts (Ganglion) 12/2017 - 10/2013
2	Ischemia 01/2016 - 12/2012
2	Retinal Degeneration 12/2010 - 10/2010
2	Neuroblastoma 05/2010 - 04/2002
2	Pheochromocytoma 05/2010 - 10/2005
2	Prostatic Neoplasms (Prostate Cancer) 05/2010 - 12/2007
1	Amyloid Plaque 01/2022
1	Lymphatic Metastasis 12/2021
1	COVID-19 11/2021
1	Hearing Disorders (Hearing Disorder) 01/2019
1	Down Syndrome (Down's Syndrome) 01/2019
1	Hearing Loss (Hearing Impairment) 01/2019
1	Hidden Hearing Loss 01/2019
1	Retinal Diseases 01/2018
1	Gliosis 01/2017
1	Pathologic Neovascularization 01/2016
1	Intractable Pain 01/2015
1	Visceral Pain 01/2015
1	Pain (Aches) 01/2015
1	Dry Eye Syndromes (Dry Eye Syndrome) 10/2011
1	Cataract (Cataracts) 07/2011
1	Optic Nerve Injuries 12/2010
1	Glioblastoma (Glioblastoma Multiforme) 05/2010
1	Carcinogenesis 05/2010
1	Medulloblastoma 05/2010

Drug/Important Bio-Agent (IBA)

11	Retinaldehyde (Retinal)IBA 01/2018 - 02/2004
9	Nerve Growth Factor (NGF)IBA 01/2022 - 04/2002
9	Proteins (Proteins, Gene)FDA Link 11/2021 - 06/2004
5	Monoclonal AntibodiesIBA 01/2019 - 06/2005
5	LigandsIBA 12/2017 - 09/2004
4	trkA ReceptorIBA 01/2022 - 02/2004
4	Nerve Growth Factors (Neurotrophins)IBA 11/2021 - 02/2004
3	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 12/2021 - 10/2005
3	AntigensIBA 01/2021 - 12/2007
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 02/2004
3	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 12/2010 - 02/2004
3	Pharmaceutical PreparationsIBA 05/2010 - 12/2007
2	Phosphotransferases (Kinase)IBA 12/2021 - 12/2010
2	VaccinesIBA 11/2021 - 01/2019
2	CarbohydratesIBA 01/2020 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 07/2011
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2020 - 04/2014
2	Tumor Biomarkers (Tumor Markers)IBA 01/2019 - 06/2004
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 04/2014
2	Streptozocin (Streptozotocin)FDA Link 01/2017 - 01/2016
2	CytokinesIBA 01/2016 - 09/2005
2	Biological ProductsIBA 01/2016 - 12/2010
2	Protein Isoforms (Isoforms)IBA 01/2016 - 12/2010
2	Pregnancy-Associated alpha 2-Macroglobulins (alpha 2 Macroglobulin)IBA 07/2011 - 10/2008
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2007 - 02/2004
2	Cholinergic Agents (Cholinergics)IBA 12/2005 - 10/2004
2	Growth Factor ReceptorsIBA 09/2004 - 06/2004
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Eukaryotic Initiation Factor-4EIBA 01/2021
1	Polysaccharides (Glycans)IBA 01/2020
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2020
1	GlycolipidsIBA 01/2019
1	Synthetic Vaccines (Recombinant Vaccines)IBA 01/2019
1	GangliosidesIBA 01/2019
1	Rhodopsin (Visual Purple)IBA 12/2017
1	Oxygen (Dioxygen)IBA 01/2016
1	Semaphorin-3AIBA 01/2016
1	EpitopesIBA 01/2016
1	Morphine (MS Contin)FDA LinkGeneric 01/2015
1	Tyrosine (L-Tyrosine)FDA Link 04/2014
1	Glial Fibrillary Acidic ProteinIBA 10/2013
1	IntegrinsIBA 12/2012
1	GD2 gangliosideIBA 01/2012
1	GlycosphingolipidsIBA 01/2012
1	PeptidomimeticsIBA 10/2011
1	Scopolamine (Hyoscine)FDA Link 10/2011
1	GlycoconjugatesIBA 10/2011
1	Immunologic Factors (Immunomodulators)IBA 12/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2010
1	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 10/2008
1	trabecular meshwork-induced glucocorticoid response proteinIBA 08/2008
1	Caveolin 1IBA 01/2008
1	Fluorescein-5-isothiocyanate (FITC)IBA 01/2008
1	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 01/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2008

Therapy/Procedure

13	Therapeutics 01/2022 - 06/2004
3	Axotomy 10/2010 - 10/2009
1	Immunotherapy 01/2021
1	Intravitreal Injections 01/2018
1	Injections 01/2017
1	Drug Therapy (Chemotherapy) 05/2010
1	Intravenous Injections 01/2008